Nesiritide (acetate)

药理：Nesiritide is a 32-amino acid natriuretic peptide and recombinant form of human brain natriuretic peptide .1 It increases ex vivo vasorelaxation induced by the calcium ionophore A23187 in porcine hearts isolated from a model of acute coronary occlusion when administered as a 2µg/kg bolus dose followed by 0.01µg/kg per minute infusion.2 Formulations containing nesiritide have previously been used in the treatment of congestive heart failure.

溶解度：Water: soluble