GSK484 hydrochloride (GTPL8577)

研究领域：Cancer; Inflammation/Immunology; Cardiovascular Disease
靶点：IC50:50 nM (PAD4, in the absence of Calcium), 250 nM (PAD4, in the presence of 2 mM Calcium)
描述：GSK484 hydrochloride (GTPL8577) is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride (GTPL8577) demonstrates high affinity binding to PAD4 with IC50s of 50
溶解性：DMSO:62.5mg/mL(122.54 mM; Need ultrasonic)
保存方式：4℃, stored under nitrogen. In solvent : -80℃, 6months; -20℃, 1month (protect from light, stored under nitrogen)