GNF-5837

研究领域：Cancer
靶点：IC50 Value:7/9/11 nM (Tel-TrkC/Tel-TrkB/Tel-TrkA) [1] Target:pan-Trk GNF-5837 is an orally bioavailable oxindole compound that and acts as a potent, reversible and type II DFG-out inhibitor of pan-
描述：GNF-5837 is a potent pan-Trk inhibitor which display antiproliferative effects in cellular Ba/F3 assays (IC50 values are 7, 9 and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and
溶解性：DMSO
保存方式：Powder -20℃ 3years; 4℃ 2years In solvent -80℃ 6months;-20℃ 1month