Fimepinostat (CUDC-907)

研究领域：Cancer
靶点：PI3Kα, 19 nM (IC50); PI3Kβ, 54 nM (IC50); PI3Kδ, 39 nM (IC50); PI3Kγ, 311 nM (IC50); HDAC1, 1.7 nM (IC50); HDAC2, 5 nM (IC50); HDAC3, 1.8 nM (IC50); HDAC4, 409 nM (IC50); HDAC5, 674 nM (IC50); HDAC6,
描述：Fimepinostat (CUDC-907) potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes with an IC50 of 19/54/39 nM and 1.7/5.0/1.8/2.8 nM for PI3Kα/PI3Kβ/PI3Kδ and HDAC1/HDAC2/HDAC3/HDAC10 ,
溶解性：DMSO
保存方式：Powder -20℃ 3years; 4℃ 2years In solvent -80℃ 6months;-20℃ 1month