Ro 31-8220 mesylate (Ro 31-8220 methanesulfonate; Bisindolylmaleimide IX mesylate)

研究领域：Neurological Disease/Cardiovascular Disease
靶点：IC50:5 nM (PKCα), 24 nM (PKCβI), 14 nM (PKCβII), 27 nM (PKCγ), 24 nM (PKCε), 23 nM (Rat brain PKC)[1], 3 nM (MAPKAP-K1b), 8 nM (MSK1), 15 nM (S6K1), 38 nM (GSK3β)[2]
描述：Ro 31-8220 mesylate is a potent PKC inhibitor, with IC50 of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPK
溶解性：DMSO
保存方式：Powder -20℃ 3years; 4℃ 2years In solvent -80℃ 6months;-20℃ 1month